Screw Ribbon Mixer Enables Efficient and High-Quality Production of Probiotic Powder

A biotech company's core product, probiotic powder, demands extremely high mixing uniformity. Low active ingredient concentration and uneven distribution directly impact product potency. Existing equipment required lengthy mixing times (30 minutes) while uniformity remained suboptimal, hindering large-scale production efficiency.

The company adopted a customized horizontal ribbon mixer. Its core feature is a dual-ribbon structure where inner and outer ribbons rotate in opposite directions, simultaneously generating powerful axial and radial flow to achieve three-dimensional mixing.

• High Uniformity and Efficiency: The dual-ribbon design ensures even distribution of even trace ingredients. Mixing time was reduced from 30 to 15 minutes, doubling efficiency.
• Gentle yet Thorough Mixing: The screw action is mild, preserving probiotic viability. The equipment features smooth, dead-zone-free inner walls and can be manufactured to GMP standards, supporting CIP-in-place cleaning to eliminate cross-batch contamination.
• Sealed, Dust-Free, and Compliant: The entire mixing process operates under sealed conditions with vacuum feeding, preventing dust leakage. This protects the workshop environment and employee health while meeting the pharmaceutical industry's stringent safety and environmental requirements.

After implementation, mixing uniformity reached 99.2%, ensuring absolute consistency of active ingredients per gram of product. The significant boost in production efficiency also met the market demand for large-scale supply.

This case study concretely demonstrates the core value of the ribbon mixer: it safeguards the quality foundation of pharmaceuticals (especially low-dose active ingredient products) through exceptionally high mixing uniformity; enhances efficiency while preserving material properties via rapid, gentle mixing; and directly meets the pharmaceutical industry's stringent GMP regulations through its easy-to-clean and sealed design. Therefore, for pharmaceutical companies like Microcon Biotech with high standards for quality, efficiency, and compliance, the screw ribbon mixer offers a highly reliable solution.